If your phone case has both a plastic and silicon component, separate the two parts. Pull the flexible silicon piece out of the hard plastic piece that’s on the outside of the case.

If you’re cleaning a leather phone case, use a drop of natural baby soap or gentle hand soap instead. If you don’t have a gentle soap, mix water and vinegar—one part vinegar, two parts water. [1] X Research source If your phone case is made from real wood, avoid using soap at all. Just use plain water or wood cleaner. If using wood cleaner, dab or spray it onto a microfiber cloth. Avoid using window cleaners, solvents, cleaners containing ammonia or hydrogen peroxide, or abrasives on all case materials. [2] X Research source

No matter the material of your phone case, you can also use a rag or sponge instead of a toothbrush. If cleaning leather or wood, wring the rag out as much as possible before applying it to the phone case.

Avoid scrubbing vigorously, especially on leather cases—if there is paint or dye in the material, a tough scrubbing can remove the color. [3] X Trustworthy Source Consumer Reports Nonprofit organization dedicated to consumer advocacy and product testing Go to source

If you have an eyeglass-cleaning cloth or one meant for electronics screens, that will work wonderfully on all surfaces.

Clean the phone case with soap and water whenever it looks dirty or you notice stains on it.

If the rubbing alcohol you’re using is in a spray bottle, spray it onto the cloth rather than the case. Alcohol can discolor leather over time, but as long as you use a small amount (don’t saturate the cloth!) you usually won’t notice a change.

You can disinfect silicone, rubber, plastic, and wood as often as you’d like. Since alcohol can discolor leather, you can’t sanitize it with alcohol as much as other materials. Try to disinfect your case at least once a week, or more often if your phone is often exposed in places where it can become contaminated. If you’re using a leather case, consider switching to a case that can easily be cleaned and disinfected, such as silicone, rubber, or plastic.

If a stain is actually discoloration, you will not be able to remove it from the case.

You may not be able to remove all stains using baking soda. If you’ve been scrubbing for a while and the stain hasn’t faded, you may need to use a harsher stain remover to lift the stain. Bleach can stain your phone case, so you’ll usually want to avoid using it. However, for more difficult stains on clear or white materials, you can add a few drops of bleach to water if baking soda doesn’t work.